Reducing the adhesion of particles, media and microorganisms to stainless steel surfaces is crucial to ensuring the efficient and safe production of pharmaceutical products or foodstuffs. In addition to the design of components and systems, the surface quality produced plays a decisive role. In technical applications, mechanical processing by grinding in combination with electropolishing is a common method of surface treatment specified by the guidelines. The present study shows how the adhesion behaviour of selected particles can be influenced by specifically varying the processing parameters and the electrochemical post-treatment carried out. It can be shown that, in addition to classic surface roughness, the mechanical processing used and the individual manufacturing steps applied there have a significant influence. The study also illustrates the effect of electrochemical post-treatment in conjunction with passivation of the component surface. The comparison of economic efficiency points to potential savings and development opportunities for further optimisation of manufacturing processes.